The permanent misfits are those who because of a lack of talent or some irreparable defect in body or mind cannot do the one thing for which their whole being craves. No achievement, however spectacular, in other fields can give them a sense of fulfillment. Whatever they undertake becomes a passionate pursuit; but they never arrive, never pause. They demonstrate the fact that we can never have enough of that which we really do not want, and that we run fastest and farthest when we run from ourselves.
The permanent misfits can find salvation only in a complete separation from the self; and they usually find it by losing themselves in the compact collectivity of a mass movement. By renouncing individual will, judgment and ambition, and dedicating all their powers to the service of an eternal cause, they are at last lifted off the endless treadmill which can never lead them to fulfillment.
The most incurably frustrated--and, therefore, the most vehement--among the permanent misfits are those with an unfulfilled craving for creative work. Both those who try to write, paint, compose, etcetera, and fail decisively, and those who after tasting the elation of creativeness feel a drying up of the creative flow within and know that never again will they produce aught worth while, are alike in the grip of a desperate passion. Neither fame nor power nor riches nor even monumental achievements in other fields can still their hunger. Eve the wholehearted dedication to a holy cause does not always cure them. Their unappeased hunger persists and they are likely to become the most violent extremists in the service of their holy cause.
Eric Hoffer - The True Believer